Difluoroalkylation of tertiary amides and lactams by an iridium-catalyzed reductive reformatsky reaction

Difluoroalkylation of tertiary amides and lactams by an iridium-catalyzed reductive reformatsky reaction

An iridium-catalyzed, reductive alkylation of abundant tertiary lactams and amides using 1-2 mol % of Vaska's complex (IrCl(CO)(PPh<sub>3</sub>)<sub>2</sub>), tetramethyldisiloxane (TMDS), and difluoro-Reformatsky reagents (BrZnCF<s...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид:	Biallas, P, Yamazaki, K, Dixon, DJ
Формат:	Journal article
Хэл сонгох:	English
Хэвлэсэн:	ACS Publications 2022

Ижил төстэй зүйлс

General pyrrolidine synthesis via iridium-catalyzed reductive azomethine ylide generation from tertiary amides and lactams
-н: Yamazaki, K, зэрэг
Хэвлэсэн: (2021)

Iridium-catalyzed reductive Strecker reaction for late-stage amide and lactam cyanation
-н: de Arriba, A, зэрэг
Хэвлэсэн: (2017)

Iridium-catalyzed reductive Strecker reaction for late-stage amide and lactam cyanation
-н: Fuentes de Arriba, Á, зэрэг
Хэвлэсэн: (2017)

Iridium-catalyzed reductive Ugi-type reactions of tertiary amides
-н: Xie, L, зэрэг
Хэвлэсэн: (2018)

Iridium-catalyzed reductive Ugi-type reactions of tertiary amides
-н: Lan-Gui Xie, зэрэг
Хэвлэсэн: (2018-07-01)

Copper-Catalyzed Difluoroalkylation Reaction
-н: Dao-Qing Dong, зэрэг
Хэвлэсэн: (2022-12-01)

Iridium-catalyzed aza-spirocyclization of indole-tethered amides: an interrupted Pictet–Spengler reaction
-н: Gabriel, P, зэрэг
Хэвлэсэн: (2019)

Cobalt-catalyzed difluoroalkylation of tertiary aryl ketones for facile synthesis of quaternary alkyl difluorides
-н: Chao Li, зэрэг
Хэвлэсэн: (2018-11-01)

Iridium-catalyzed reductive allylation of esters
-н: Xie, L, зэрэг
Хэвлэсэн: (2019)

Iridium-catalyzed reductive nitro-Mannich cyclization.
-н: Gregory, A, зэрэг
Хэвлэсэн: (2015)

General α-amino 1,3,4-oxadiazole synthesis via late-stage reductive functionalization of tertiary amides and lactams
-н: Matheau-Raven, D, зэрэг
Хэвлэсэн: (2021)

Recent developments in the asymmetric Reformatsky-type reaction
-н: Hélène Pellissier
Хэвлэсэн: (2018-02-01)

Copper‐Catalyzed Regio‐ and Enantioselective Hydroboration of Difluoroalkyl‐Substituted Internal Alkenes
-н: Tao‐Qian Zhao, зэрэг
Хэвлэсэн: (2023-12-01)

Carbohydrate-derived aminoalcohol ligands for asymmetric Reformatsky reactions
-н: Emmerson, D, зэрэг
Хэвлэсэн: (2005)

Enantioselective total synthesis of (+)-incargranine A enabled by bifunctional iminophosphorane and iridium catalysis
-н: Miller, AAM, зэрэг
Хэвлэсэн: (2023)

Enantioselective total synthesis of (+)-incargranine A enabled by bifunctional iminophosphorane and iridium catalysis
-н: Miller, AAM, зэрэг
Хэвлэсэн: (2023)

Photoredox-catalyzed intramolecular nucleophilic amidation of alkenes with β-lactams
-н: Valentina Giraldi, зэрэг
Хэвлэсэн: (2024-10-01)

A general iridium-catalyzed reductive dienamine synthesis allows a five-step synthesis of catharanthine via the elusive dehydrosecodine
-н: Gabriel, P, зэрэг
Хэвлэсэн: (2021)

Recent Developments in the Reformatsky-Claisen Rearrangement
-н: Susumi Hatakeyama, зэрэг
Хэвлэсэн: (2012-11-01)

Palladium-Catalyzed Intramolecular C-H Difluoroalkylation: Synthesis of Substituted 3,3-Difluoro-2-oxindoles
-н: Shi, Shi-Liang, зэрэг
Хэвлэсэн: (2015)

Bifunctional iminophosphorane-catalyzed enantioselective sulfa-michael addition to unactivated α,β-unsaturated amides
-н: Rozsar, D, зэрэг
Хэвлэсэн: (2022)

Highly Catalytic Enantioselective Reformatsky Reaction with Aldehydes and Ketones Using an Available Prolinol Ligand
-н: Lu Ouyang, зэрэг
Хэвлэсэн: (2020-06-01)

Iridium-Catalyzed and pH-Dependent Reductions of Nitroalkenes to Ketones
-н: Tingting Wang, зэрэг
Хэвлэсэн: (2022-11-01)

Enantioselective silver-catalyzed cascade synthesis of fused lactone and lactam oxazolines
-н: De La Campa, R, зэрэг
Хэвлэсэн: (2018)

Efficient reformatsky conjugate additions to alkylidene malonates and malonamides
-н: Bentz, E, зэрэг
Хэвлэсэн: (2007)

Visible light-mediated difluoroalkylation of electron-deficient alkenes
-н: Vyacheslav I. Supranovich, зэрэг
Хэвлэсэн: (2018-07-01)

REFORMATSKY-TYPE REACTION WITH NEW CALCIUM REAGENTS BY USING CALCIUM ATOM - THF CO-CONDENSATES
-н: Yokoyama†, Yasuo, зэрэг
Хэвлэсэн: (2000-11-01)

Iridium-Catalyzed asymmetric reduction of α,β-Unsaturated nitriles with water
-н: Qinli Lu, зэрэг
Хэвлэсэн: (2024-08-01)

Amide nitrogen pyramidalization changes lactam amide spinning
-н: Yuko Otani, зэрэг
Хэвлэсэн: (2019-01-01)

Iridium(III)-catalyzed selective and mild C-H amidation of cyclic N-sulfonyl ketimines with organic azides
-н: Maraswami, Manikantha, зэрэг
Хэвлэсэн: (2019)

Bifunctional iminophosphorane catalyzed amide enolization for enantioselective cyclohexadienone desymmetrization.
-н: Poh, CYX, зэрэг
Хэвлэсэн: (2023)

Functionalised pyrrolidinones by conjugate addition of stabilised enolates and reformatsky reagents
-н: Dyer, J, зэрэг
Хэвлэсэн: (1996)

Synthesis of enones, pyrazolines and pyrrolines with gem-difluoroalkyl side chains
-н: Assaad Nasr El Dine, зэрэг
Хэвлэсэн: (2013-09-01)

Hydrogen-Borrowing and Interrupted-Hydrogen-Borrowing Reactions of Ketones and Methanol Catalyzed by Iridium.
-н: Shen, D, зэрэг
Хэвлэсэн: (2014)

Hydrogen-borrowing and interrupted-hydrogen-borrowing reactions of ketones and methanol catalyzed by iridium
-н: Shen, D, зэрэг
Хэвлэсэн: (2015)

Catalytic enantioselective intramolecular oxa-Michael reaction to α,β-unsaturated esters and amides
-н: Su, G, зэрэг
Хэвлэсэн: (2023)

1,2-redox transpositions of tertiary amides
-н: Shennan, BDA, зэрэг
Хэвлэсэн: (2023)

Tertiary amine synthesis via reductive coupling of amides with Grignard reagents
-н: Xie, L, зэрэг
Хэвлэсэн: (2017)

Synthesis of Amides and Lactams in Supercritical Carbon Dioxide
-н: Mak, Xiao Yin, зэрэг
Хэвлэсэн: (2011)

Iridium-catalyzed asymmetric ring-opening reactions of oxabicyclic alkenes with secondary amine nucleophiles
-н: Dingqiao Yang, зэрэг
Хэвлэсэн: (2009-10-01)