Biochemical assessment of serotonergic and cholinergic dysfunction and cerebral atrophy in Alzheimer's disease.

Biochemical assessment of serotonergic and cholinergic dysfunction and cerebral atrophy in Alzheimer's disease.

Markers of serotonin synapses in entire temporal lobe and frontal and temporal neocortex were examined for changes in Alzheimer's disease by use of both neurosurgical and autopsy samples. Uptake of [3H]serotonin, binding of [3H]imipramine, and content of indolamines were all significantly reduc...

Volledige beschrijving

Bibliografische gegevens
Hoofdauteurs:	Bowen, D, Allen, S, Benton, J, Goodhardt, M, Haan, E, Palmer, A, Sims, N, Smith, C, Spillane, J, Esiri, M, Neary, D, Snowdon, J, Wilcock, G, Davison, A
Formaat:	Journal article
Taal:	English
Gepubliceerd in:	1983

Gelijkaardige items

Neurotransmitter dysfunction and atrophy of the caudate nucleus in Alzheimer's disease.
door: Pearce, B, et al.
Gepubliceerd in: (1984)

Imbalance of a serotonergic system in frontotemporal dementia: implication for pharmacotherapy.
door: Bowen, D, et al.
Gepubliceerd in: (2008)

Neurochemical studies of early-onset Alzheimer's disease. Possible influence on treatment.
door: Francis, P, et al.
Gepubliceerd in: (1985)

Complementary roles of serotonergic and cholinergic systems in decisions about when to act
door: Khalighinejad, N, et al.
Gepubliceerd in: (2022)

Caveolin-3 differentially orchestrates cholinergic and serotonergic constriction of murine airways
door: M. Keshavarz, et al.
Gepubliceerd in: (2018-05-01)

The cholinergic hypothesis of Alzheimer's disease: a review of progress.
door: Francis, P, et al.
Gepubliceerd in: (1999)

Treatment of the cholinergic impairment in Alzheimer's disease
door: Wilcock, G
Gepubliceerd in: (1994)

Common Cholinergic, Noradrenergic, and Serotonergic Drugs Do Not Block VNS-Mediated Plasticity
door: Robert A. Morrison, et al.
Gepubliceerd in: (2022-02-01)

The cholinergic hypothesis of Alzheimer's disease: a review of progress - Reply
door: Francis, P, et al.
Gepubliceerd in: (1999)

CHOLINERGIC, CATECHOLAMINERGIC, SEROTONERGIC, AND OREXINERGIC NEURONAL POPULATIONS IN THE BRAIN OF THE LESSER HEDGEHOG TENREC (ECHINOPS TELFAIRI)
door: Illke Bianca Malungo, et al.
Gepubliceerd in: (2023-10-01)

Monoaminergic innervation of the frontal and temporal lobes in Alzheimer's disease.
door: Palmer, A, et al.
Gepubliceerd in: (1987)

Cholinergic side-effects of tetrahydroaminoacridine.
door: Wilcock, G, et al.
Gepubliceerd in: (1988)

Cholinesterase activities in cerebrospinal fluid of patients with senile dementia of Alzheimer type.
door: Appleyard, M, et al.
Gepubliceerd in: (1987)

The Nerve Growth Factor Metabolic Pathway Dysregulation as Cause of Alzheimer’s Cholinergic Atrophy
door: Sonia Do Carmo, et al.
Gepubliceerd in: (2021-12-01)

Persistence of cholinergic neurons in the basal nucleus in a brain with senile dementia of the Alzheimer's type demonstrated by immunohistochemical staining for choline acetyltransferase.
door: Pearson, R, et al.
Gepubliceerd in: (1983)

THE RELATIONSHIP OF ARGYROPHILIC PLAQUES AND NEUROFIBRILLARY TANGLES TO THE SEVERITY OF DEMENTIA AND CORTICAL CHOLINE ACETYL TRANSFERASE LEVELS IN ALZHEIMERS-DISEASE
door: Wilcock, G, et al.
Gepubliceerd in: (1983)

Biochemical studies on muscarinic cholinergic receptors
door: Carson, S
Gepubliceerd in: (1982)

Cholinergic basal forebrain atrophy in Parkinson's disease with freezing of gait
door: Caiting Gan, et al.
Gepubliceerd in: (2023-05-01)

Reduced cholinergic function in normal and Alzheimer's disease brain is associated with apolipoprotein E4 genotype.
door: Allen, S, et al.
Gepubliceerd in: (1997)

Cholinergic denervation exacerbates amyloid pathology and induces hippocampal atrophy in Tg2576 mice
door: Francisco J. Gil-Bea, et al.
Gepubliceerd in: (2012-12-01)

Orexin receptor activation generates gamma band input to cholinergic and serotonergic arousal system neurons and drives an intrinsic Ca2+-dependent resonance in LDT and PPT cholinergic neurons.
door: Masaru eIshibashi, et al.
Gepubliceerd in: (2015-06-01)

The nucleus basalis in Alzheimer's disease: cell counts and cortical biochemistry.
door: Wilcock, G, et al.
Gepubliceerd in: (1983)

The differential involvement of subcortical nuclei in senile dementia of Alzheimer's type.
door: Wilcock, G, et al.
Gepubliceerd in: (1988)

Cholinergic deficits contribute to behavioral disturbance in patients with dementia.
door: Minger, S, et al.
Gepubliceerd in: (2000)

Alzheimer's disease. Correlation of cortical choline acetyltransferase activity with the severity of dementia and histological abnormalities.
door: Wilcock, G, et al.
Gepubliceerd in: (1982)

β-Amyloid(1-42)-Induced Cholinergic Lesions in Rat Nucleus Basalis Bidirectionally Modulate Serotonergic Innervation of the Basal Forebrain and Cerebral Cortex
door: Tibor Harkany, et al.
Gepubliceerd in: (2001-08-01)

A pilot study of serotonin-1A receptor genotypes and rapid eye movement sleep sensitivity to serotonergic/cholinergic imbalance in humans: a pharmacological model of depression
door: Biard K, et al.
Gepubliceerd in: (2015-12-01)

Age and Alzheimer's disease.
door: Wilcock, G, et al.
Gepubliceerd in: (1983)

APOE epsilon 4 allele affects presynaptic, but not postsynaptic cholinergic markers in Alzheimer's disease neocortex
door: Lai, M, et al.
Gepubliceerd in: (2006)

Selective effects of the APOE epsilon4 allele on presynaptic cholinergic markers in the neocortex of Alzheimer's disease.
door: Lai, M, et al.
Gepubliceerd in: (2006)

Asymmetry of pathology in Alzheimer's disease.
door: Wilcock, G, et al.
Gepubliceerd in: (1987)

The olfactory bulbs in Alzheimer's disease.
door: Esiri, M, et al.
Gepubliceerd in: (1984)

Cholinergic brainstem neurons modulate cortical gamma activity during slow oscillations.
door: Mena-Segovia, J, et al.
Gepubliceerd in: (2008)

Cholinergic brainstem neurons modulate cortical gamma activity during slow oscillations
door: Mena-Segovia, J, et al.
Gepubliceerd in: (2008)

Serotonergic dysfunction may mediate the relationship between alcohol consumption and Alzheimer’s disease
door: Samantha R. Pierson, et al.
Gepubliceerd in: (2024-05-01)

Serotonergic modulation of the claustrum
door: Wong, Kelly Li Lin
Gepubliceerd in: (2022)

Behavioral correlates of the activity of serotonergic and non-serotonergic neurons in caudal raphe nuclei
door: L.E. Ribeiro-do-Valle, et al.
Gepubliceerd in: (2001-07-01)

The role of the serotonergic system in suicidal behavior
door: Sadkowski M, et al.
Gepubliceerd in: (2013-11-01)

A Single Pair of Serotonergic Neurons Counteracts Serotonergic Inhibition of Ethanol Attraction in Drosophila.
door: Li Xu, et al.
Gepubliceerd in: (2016-01-01)

Pathologic diagnosis of Alzheimer's.
door: Köster, R, et al.
Gepubliceerd in: (1989)