Chromosomal translocation products engender new intracellular therapeutic technologies.

Chromosomal translocations occur in leukemias, lymphomas, sarcomas and some epithelial tumors and some generate unique fusion proteins. These translocation products may provide tumor-specific targets for the development of new therapeutic strategies tailored to a malignant cell.

Detalhes bibliográficos
Main Authors: Rabbitts, T, Stocks, MR
Formato: Journal article
Idioma:English
Publicado em: 2003
Descrição
Resumo:Chromosomal translocations occur in leukemias, lymphomas, sarcomas and some epithelial tumors and some generate unique fusion proteins. These translocation products may provide tumor-specific targets for the development of new therapeutic strategies tailored to a malignant cell.