Designing a new cross-linkable cohesin complex for studying cohesin`s interaction with DNA

<p>Sister chromatid cohesion is essential for accurate chromosome segregation. Cohesion is generated by cohesin, a conserved multi-subunit protein complex composed of four core subunits: Smc1, Smc3, Scc1, and Scc3. Cohesin holds sister chromatids together in mitotic cells starting from S-phase...

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Bibliographic Details
Main Author: Uluocak, P
Other Authors: Nasmyth, K
Format: Thesis
Language:English
Published: 2012
Subjects: