Designing a new cross-linkable cohesin complex for studying cohesin`s interaction with DNA
<p>Sister chromatid cohesion is essential for accurate chromosome segregation. Cohesion is generated by cohesin, a conserved multi-subunit protein complex composed of four core subunits: Smc1, Smc3, Scc1, and Scc3. Cohesin holds sister chromatids together in mitotic cells starting from S-phase...
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Format: | Thesis |
Language: | English |
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2012
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