Designing a new cross-linkable cohesin complex for studying cohesin`s interaction with DNA

Designing a new cross-linkable cohesin complex for studying cohesin`s interaction with DNA

<p>Sister chromatid cohesion is essential for accurate chromosome segregation. Cohesion is generated by cohesin, a conserved multi-subunit protein complex composed of four core subunits: Smc1, Smc3, Scc1, and Scc3. Cohesin holds sister chromatids together in mitotic cells starting from S-phase...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awdur:	Uluocak, P
Awduron Eraill:	Nasmyth, K
Fformat:	Traethawd Ymchwil
Iaith:	English
Cyhoeddwyd:	2012
Pynciau:	Life Sciences Biochemistry

Eitemau Tebyg

Biochemical studies of the cohesin complex
gan: Upcher, WR
Cyhoeddwyd: (2012)

Biochemical study of the interactions between cohesin and DNA
gan: Collier, JE
Cyhoeddwyd: (2020)

A microscopic study of cohesin
gan: Rhodes, J
Cyhoeddwyd: (2017)

Investigating the function and regulation of cohesin ATPase
gan: Voulgaris, M
Cyhoeddwyd: (2021)

Towards understanding the mechanism of cohesin loading
gan: Dixon, SE
Cyhoeddwyd: (2013)

How do sister DNAs become entrapped within cohesin rings?
gan: Laurent, CM
Cyhoeddwyd: (2022)

The ATPases of cohesin interface with regulators to modulate cohesin-mediated DNA tethering
gan: Gamze Çamdere, et al.
Cyhoeddwyd: (2015-11-01)

Cohesin's concatenation of sister DNAs maintains their intertwining.
gan: Farcas, A, et al.
Cyhoeddwyd: (2011)

How does the loading complex interact with cohesin?
gan: Metson, J
Cyhoeddwyd: (2021)

Cohesin-interacting protein WAPL-1 regulates meiotic chromosome structure and cohesion by antagonizing specific cohesin complexes
gan: Oliver Crawley, et al.
Cyhoeddwyd: (2016-02-01)

A conserved domain in the scc3 subunit of cohesin mediates the interaction with both mcd1 and the cohesin loader complex.
gan: Ola Orgil, et al.
Cyhoeddwyd: (2015-03-01)

Different NIPBL requirements of cohesin-STAG1 and cohesin-STAG2
gan: Dácil Alonso-Gil, et al.
Cyhoeddwyd: (2023-03-01)

Cohesin-Mediated Chromatin Interactions and Autoimmunity
gan: Venkataragavan Chandrasekaran, et al.
Cyhoeddwyd: (2022-02-01)

The cohesin ring concatenates sister DNA molecules.
gan: Haering, C, et al.
Cyhoeddwyd: (2008)

The loopy world of cohesin
gan: Kazuhiro Maeshima, et al.
Cyhoeddwyd: (2021-07-01)

Effect of CTCF and Cohesin on the dynamics of RNA polymerase II transcription and coupled pre-messenger RNA processing
gan: Liska, O
Cyhoeddwyd: (2013)

A Brownian ratchet model for DNA loop extrusion by the cohesin complex
gan: Torahiko L Higashi, et al.
Cyhoeddwyd: (2021-07-01)

A dual role of Cohesin in DNA DSB repair
gan: Michael Fedkenheuer, et al.
Cyhoeddwyd: (2025-01-01)

Cohesin: Not Just Important in Mitosis!
gan: Pauli, A, et al.
Cyhoeddwyd: (2010)

Cohesin: its roles and mechanisms.
gan: Nasmyth, K, et al.
Cyhoeddwyd: (2009)

Cohesin architecture and clustering in vivo
gan: Siheng Xiang, et al.
Cyhoeddwyd: (2021-02-01)

The multifaceted roles of cohesin in cancer
gan: Maddalena Di Nardo, et al.
Cyhoeddwyd: (2022-03-01)

Taking cohesin and condensin in context.
gan: Kobe C Yuen, et al.
Cyhoeddwyd: (2018-01-01)

Sister DNA entrapment between juxtaposed Smc heads and kleisin of the cohesin complex
gan: Chapard, C, et al.
Cyhoeddwyd: (2019)

The Cohesin Complex and Its Interplay with Non-Coding RNAs
gan: Merve Kuru-Schors, et al.
Cyhoeddwyd: (2021-10-01)

Cohesin Can Remain Associated with Chromosomes during DNA Replication
gan: James D.P. Rhodes, et al.
Cyhoeddwyd: (2017-09-01)

Structure of the cohesin loader Scc2
gan: William C. H. Chao, et al.
Cyhoeddwyd: (2017-01-01)

Cohesin can remain associated with chromosomes during DNA replication
gan: Rhodes, J, et al.
Cyhoeddwyd: (2017)

The Interplay of Cohesin and the Replisome at Processive and Stressed DNA Replication Forks
gan: Janne J. M. van Schie, et al.
Cyhoeddwyd: (2021-12-01)

CTCF, Cohesin, and Chromatin in Human Cancer
gan: Sang-Hyun Song, et al.
Cyhoeddwyd: (2017-12-01)

The consequences of cohesin mutations in myeloid malignancies
gan: Shubhra Ashish Bhattacharya, et al.
Cyhoeddwyd: (2023-11-01)

It’s all in the numbers: Cohesin stoichiometry
gan: Avi Matityahu, et al.
Cyhoeddwyd: (2022-10-01)

Cohesin is required for activation of MYC by estradiol.
gan: Miranda V McEwan, et al.
Cyhoeddwyd: (2012-01-01)

The kinetochore is an enhancer of pericentric cohesin binding.
gan: Stewart A Weber, et al.
Cyhoeddwyd: (2004-09-01)

Specific Contributions of Cohesin-SA1 and Cohesin-SA2 to TADs and Polycomb Domains in Embryonic Stem Cells
gan: Ana Cuadrado, et al.
Cyhoeddwyd: (2019-06-01)

Cohesin complexes with a potential to link mammalian meiosis to cancer
gan: Alexander Strunnikov
Cyhoeddwyd: (2013-01-01)

Developing a peptide to disrupt cohesin head domain interactions
gan: Maria Elias, et al.
Cyhoeddwyd: (2023-09-01)

MCM complexes are barriers that restrict cohesin-mediated loop extrusion
gan: Dequeker, Bart JH, et al.
Cyhoeddwyd: (2023)

Distinct Roles of Meiosis-Specific Cohesin Complexes in Mammalian Spermatogenesis.
gan: Uddipta Biswas, et al.
Cyhoeddwyd: (2016-10-01)

Genome-wide mapping of the cohesin complex in the yeast Saccharomyces cerevisiae.
gan: Earl F Glynn, et al.
Cyhoeddwyd: (2004-09-01)