Designing a new cross-linkable cohesin complex for studying cohesin`s interaction with DNA

Designing a new cross-linkable cohesin complex for studying cohesin`s interaction with DNA

<p>Sister chromatid cohesion is essential for accurate chromosome segregation. Cohesion is generated by cohesin, a conserved multi-subunit protein complex composed of four core subunits: Smc1, Smc3, Scc1, and Scc3. Cohesin holds sister chromatids together in mitotic cells starting from S-phase...

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Bibliografische gegevens
Hoofdauteur:	Uluocak, P
Andere auteurs:	Nasmyth, K
Formaat:	Thesis
Taal:	English
Gepubliceerd in:	2012
Onderwerpen:	Life Sciences Biochemistry

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How does the loading complex interact with cohesin?
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A conserved domain in the scc3 subunit of cohesin mediates the interaction with both mcd1 and the cohesin loader complex.
door: Ola Orgil, et al.
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Different NIPBL requirements of cohesin-STAG1 and cohesin-STAG2
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Gepubliceerd in: (2022-02-01)

The cohesin ring concatenates sister DNA molecules.
door: Haering, C, et al.
Gepubliceerd in: (2008)

The loopy world of cohesin
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Effect of CTCF and Cohesin on the dynamics of RNA polymerase II transcription and coupled pre-messenger RNA processing
door: Liska, O
Gepubliceerd in: (2013)

A Brownian ratchet model for DNA loop extrusion by the cohesin complex
door: Torahiko L Higashi, et al.
Gepubliceerd in: (2021-07-01)

A dual role of Cohesin in DNA DSB repair
door: Michael Fedkenheuer, et al.
Gepubliceerd in: (2025-01-01)

Cohesin: Not Just Important in Mitosis!
door: Pauli, A, et al.
Gepubliceerd in: (2010)

Cohesin: its roles and mechanisms.
door: Nasmyth, K, et al.
Gepubliceerd in: (2009)

Cohesin architecture and clustering in vivo
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The multifaceted roles of cohesin in cancer
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Taking cohesin and condensin in context.
door: Kobe C Yuen, et al.
Gepubliceerd in: (2018-01-01)

Sister DNA entrapment between juxtaposed Smc heads and kleisin of the cohesin complex
door: Chapard, C, et al.
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The Cohesin Complex and Its Interplay with Non-Coding RNAs
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Gepubliceerd in: (2021-10-01)

Cohesin Can Remain Associated with Chromosomes during DNA Replication
door: James D.P. Rhodes, et al.
Gepubliceerd in: (2017-09-01)

Structure of the cohesin loader Scc2
door: William C. H. Chao, et al.
Gepubliceerd in: (2017-01-01)

Cohesin can remain associated with chromosomes during DNA replication
door: Rhodes, J, et al.
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The Interplay of Cohesin and the Replisome at Processive and Stressed DNA Replication Forks
door: Janne J. M. van Schie, et al.
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CTCF, Cohesin, and Chromatin in Human Cancer
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The consequences of cohesin mutations in myeloid malignancies
door: Shubhra Ashish Bhattacharya, et al.
Gepubliceerd in: (2023-11-01)

It’s all in the numbers: Cohesin stoichiometry
door: Avi Matityahu, et al.
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Cohesin is required for activation of MYC by estradiol.
door: Miranda V McEwan, et al.
Gepubliceerd in: (2012-01-01)

The kinetochore is an enhancer of pericentric cohesin binding.
door: Stewart A Weber, et al.
Gepubliceerd in: (2004-09-01)

Specific Contributions of Cohesin-SA1 and Cohesin-SA2 to TADs and Polycomb Domains in Embryonic Stem Cells
door: Ana Cuadrado, et al.
Gepubliceerd in: (2019-06-01)

Cohesin complexes with a potential to link mammalian meiosis to cancer
door: Alexander Strunnikov
Gepubliceerd in: (2013-01-01)

Developing a peptide to disrupt cohesin head domain interactions
door: Maria Elias, et al.
Gepubliceerd in: (2023-09-01)

MCM complexes are barriers that restrict cohesin-mediated loop extrusion
door: Dequeker, Bart JH, et al.
Gepubliceerd in: (2023)

Distinct Roles of Meiosis-Specific Cohesin Complexes in Mammalian Spermatogenesis.
door: Uddipta Biswas, et al.
Gepubliceerd in: (2016-10-01)

Genome-wide mapping of the cohesin complex in the yeast Saccharomyces cerevisiae.
door: Earl F Glynn, et al.
Gepubliceerd in: (2004-09-01)