An essential role for Prox1 in the induction of the lymphatic endothelial cell phenotype.

The process of angiogenesis has been well documented, but little is known about the biology of lymphatic endothelial cells and the molecular mechanisms controlling lymphangiogenesis. The homeobox gene Prox1 is expressed in a subpopulation of endothelial cells that, after budding from veins, gives ri...

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Bibliographic Details
Main Authors: Wigle, J, Harvey, N, Detmar, M, Lagutina, I, Grosveld, G, Gunn, MD, Jackson, D, Oliver, G
Format: Journal article
Language:English
Published: 2002