Inflation vs exhaustion of antiviral CD8+ t-cell populations in persistent infections: two sides of the same coin?
Persistent virus infection can drive CD8+ T-cell responses which are markedly divergent in terms of frequency, phenotype, function, and distribution. On the one hand viruses such as Lymphocytic Choriomeningitis Virus (LCMV) Clone 13 can drive T-cell "exhaustion", associated with upregulati...
| Hlavní autoři: | , , |
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| Médium: | Journal article |
| Jazyk: | English |
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Frontiers Media
2019
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