Extracellular isoforms of CD6 generated by alternative splicing regulate targeting of CD6 to the immunological synapse.
The great majority of mammalian genes yield multiple transcripts arising from differential mRNA processing, but in very few instances have alternative forms been assigned distinct functional properties. We have cloned and characterized a new isoform of the accessory molecule CD6 that lacks the CD166...
Հիմնական հեղինակներ: | Castro, M, Oliveira, M, Nunes, R, Fabre, S, Barbosa, R, Peixoto, A, Brown, M, Parnes, JR, Bismuth, G, Moreira, A, Rocha, B, Carmo, A |
---|---|
Ձևաչափ: | Journal article |
Լեզու: | English |
Հրապարակվել է: |
2007
|
Նմանատիպ նյութեր
-
Domain‐specific CD6 monoclonal antibodies identify CD6 isoforms generated by alternative‐splicing
: Santos, R, և այլն
Հրապարակվել է: (2019) -
CD6 attenuates early and late signaling events, setting thresholds for T-cell activation.
: Oliveira, M, և այլն
Հրապարակվել է: (2012) -
The immunological synapse and CD28-CD80 interactions.
: Bromley, S, և այլն
Հրապարակվել է: (2001) -
CD28-CD80 Interactions Control Regulatory T Cell Motility and Immunological Synapse Formation.
: Thauland, T, և այլն
Հրապարակվել է: (2014) -
Immature CD4(+)CD8(+) thymocytes form a multifocal immunological synapse with sustained tyrosine phosphorylation.
: Hailman, E, և այլն
Հրապարակվել է: (2002)