Use of SSCP analysis to identify germline mutations in HNPCC families fulfilling the Amsterdam criteria.

Use of SSCP analysis to identify germline mutations in HNPCC families fulfilling the Amsterdam criteria.

Hereditary non-polyposis colorectal cancer (HNPCC) is a clinical syndrome characterised by an inherited predisposition to early onset colorectal and uterine cancers and an increased incidence of other cancers. It is caused by germline defects in the human mismatch repair genes. Defects in two of the...

书目详细资料
Main Authors:	Beck, N, Tomlinson, I, Homfray, T, Frayling, I, Hodgson, S, Harocopos, C, Bodmer, W
格式:	Journal article
语言:	English
出版:	1997

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