Dimerization of complement factor H-related proteins modulates complement activation in vivo.
The complement system is a key component regulation influences susceptibility to age-related macular degeneration, meningitis, and kidney disease. Variation includes genomic rearrangements within the complement factor H-related (CFHR) locus. Elucidating the mechanism underlying these associations ha...
Hlavní autoři: | , , , , , , , , , , |
---|---|
Médium: | Journal article |
Jazyk: | English |
Vydáno: |
2013
|