Involvement of the N-terminus of Kir6.2 in the inhibition of the KATP channel by ATP.

Involvement of the N-terminus of Kir6.2 in the inhibition of the KATP channel by ATP.

1. ATP-sensitive potassium (KATP) channels are composed of pore-forming Kir6.2 and regulatory SUR subunits. A truncated isoform of Kir6.2, Kir6.2DeltaC26, expresses ATP-sensitive channels in the absence of SUR1, suggesting the ATP-inhibitory site lies on the Kir6. 2 subunit. 2. We examined the effec...

書誌詳細
主要な著者:	Proks, P, Gribble, F, Adhikari, R, Tucker, S, Ashcroft, F
フォーマット:	Journal article
言語:	English
出版事項:	1999

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