Involvement of the N-terminus of Kir6.2 in the inhibition of the KATP channel by ATP.
1. ATP-sensitive potassium (KATP) channels are composed of pore-forming Kir6.2 and regulatory SUR subunits. A truncated isoform of Kir6.2, Kir6.2DeltaC26, expresses ATP-sensitive channels in the absence of SUR1, suggesting the ATP-inhibitory site lies on the Kir6. 2 subunit. 2. We examined the effec...
Үндсэн зохиолчид: | Proks, P, Gribble, F, Adhikari, R, Tucker, S, Ashcroft, F |
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Формат: | Journal article |
Хэл сонгох: | English |
Хэвлэсэн: |
1999
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