Molecular dynamics simulations reveal canonical conformations in different pMHC/TCR interactions

The major defense system against microbial pathogens in vertebrates is the adaptive immune response and represents an effective mechanism in cancer surveillance. T cells represent an essential component of this complex system. They can recognize myriads of antigens as short peptides (p) originated f...

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Bibliographic Details
Main Authors: Alba, J, Di Rienzo, L, Milanetti, E, Acuto, O, D'Abramo, M
Format: Journal article
Language:English
Published: MDPI 2020