Modelling toehold-mediated RNA strand displacement

We study the thermodynamics and kinetics of an RNA toehold-mediated strand displacement reaction with a recently developed coarse-grained model of RNA. Strand displacement, during which a single strand displaces a different strand previously bound to a complementary substrate strand, is an essential...

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Bibliographic Details
Main Authors: Šulc, P, Ouldridge, TE, Romano, F, Doye, JPK, Louis, AA
Format: Journal article
Language:English
Published: Cell Press 2015