BRCA2-dependent and independent formation of RAD51 nuclear foci.

The formation of RAD51 foci in response to ionizing radiation (IR) represents an important step in the repair of DNA double-strand breaks. RAD51 foci also appear during S phase and are thought to be required for the restart of stalled or broken replication forks. The RAD51 recombinase interacts dire...

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Bibliographic Details
Main Authors: Tarsounas, M, Davies, D, West, S
Format: Journal article
Language:English
Published: 2003