Dihydrofolate-reductase mutations in Plasmodium knowlesi appear unrelated to selective drug pressure from putative human-to-human transmission in Sabah, Malaysia

<p><strong>Background</strong> Malaria caused by zoonotic Plasmodium knowlesi is an emerging threat in Eastern Malaysia. Despite demonstrated vector competency, it is unknown whether human-to-human (H-H) transmission is occurring naturally. We sought evidence of drug selection pres...

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Bibliographic Details
Main Authors: Grigg, MJ, Barber, BE, Marfurt, J, Imwong, M, William, T, Bird, E, Piera, KA, Aziz, A, Boonyuen, U, Drakeley, CJ, Cox, J, White, NJ, Cheng, Q, Yeo, TW, Auburn, S, Anstey, NM
Format: Journal article
Language:English
Published: Public Library of Science 2016