NEM modification prevents high-affinity ATP binding to the first nucleotide binding fold of the sulphonylurea receptor, SUR1.

NEM modification prevents high-affinity ATP binding to the first nucleotide binding fold of the sulphonylurea receptor, SUR1.

Pancreatic beta-cell ATP-sensitive potassium channels, composed of SUR1 and Kir6.2 subunits, serve as a sensor for intracellular nucleotides and regulate glucose-induced insulin secretion. To learn more about the interaction of SUR1 with nucleotides, we examined the effect of N-ethylmaleimide (NEM)...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون:	Matsuo, M, Tucker, S, Ashcroft, F, Amachi, T, Ueda, K
التنسيق:	Journal article
اللغة:	English
منشور في:	1999

مواد مشابهة

Non-equivalent cooperation between the two nucleotide-binding folds of P-glycoprotein.
حسب: Takada, Y, وآخرون
منشور في: (1998)

Potassium channel regulation - Structural insights into the function of the nucleotide-binding domains of the human sulphonylurea receptor
حسب: Campbell, J, وآخرون
منشور في: (2003)

Interaction of MgATP with the sulphonylurea subunit activates ATP sensitive K-channels receptor
حسب: Gribble, F, وآخرون
منشور في: (1998)

Mutations in the linker domain of NBD2 of SUR inhibit transduction but not nucleotide binding.
حسب: Matsuo, M, وآخرون
منشور في: (2002)

Phentolamine block of ATP-sensitive K+ channels does not involve interaction with the sulphonylurea receptor, SUR1.
حسب: Proks, P, وآخرون
منشور في: (1997)

Functional analysis of a mutant sulphonylurea receptor associated with a mild form of persistent hyperinsulinaemic hypoglycaemia of infancy
حسب: Trapp, S, وآخرون
منشور في: (2000)

Analysis of the differential modulation of sulphonylurea block of beta-cell and cardiac ATP-sensitive K+ (K(ATP)) channels by Mg-nucleotides.
حسب: Reimann, F, وآخرون
منشور في: (2003)

Binding of sulphonylureas to plasma proteins – a KATP channel perspective
حسب: Proks, P, وآخرون
منشور في: (2018)

Binding of sulphonylureas to plasma proteins - A KATP channel perspective.
حسب: Peter Proks, وآخرون
منشور في: (2018-01-01)

Truncation of Kir6.2 produces ATP-sensitive K+ channels in the absence of the sulphonylurea receptor.
حسب: Tucker, S, وآخرون
منشور في: (1997)

Direct photoaffinity labeling of the Kir6.2 subunit of the ATP-sensitive K+ channel by 8-azido-ATP.
حسب: Tanabe, K, وآخرون
منشور في: (1999)

Activation mechanism of ATP-sensitive K+ channels explored with real-time nucleotide binding
حسب: Puljung, M, وآخرون
منشور في: (2019)

Structure and association of ATP-binding cassette transporter nucleotide-binding domains
حسب: Kerr, I
منشور في: (2002)

FoldAffinity: binding affinities from nDSF experiments
حسب: Stephan Niebling, وآخرون
منشور في: (2021-05-01)

A universally conserved residue in the SUR1 subunit of the K ATP channel is essential for translating nucleotide binding at SUR1 into channel opening
حسب: de Wet, H, وآخرون
منشور في: (2012)

Activation mechanism of ATP-sensitive K+ channels explored with real-time nucleotide binding
حسب: Michael Puljung, وآخرون
منشور في: (2019-02-01)

Molecular mechanism of sulphonylurea block of K(ATP) channels carrying mutations that impair ATP inhibition and cause neonatal diabetes.
حسب: Proks, P, وآخرون
منشور في: (2013)

Involvement of the n-terminus of Kir6.2 in coupling to the sulphonylurea receptor.
حسب: Reimann, F, وآخرون
منشور في: (1999)

High-affinity block of K-ATP channels of mouse isolated pancreatic beta-cells but not rat heart or arterial smooth muscle cells by the sulphonylurea gliclazide
حسب: Jones, P, وآخرون
منشور في: (2001)

Kir6.2-dependent high-affinity repaglinide binding to beta-cell K(ATP) channels.
حسب: Hansen, A, وآخرون
منشور في: (2005)

Studies on ATP-diphosphohydrolase nucleotide-binding sites by intrinsic fluorescence
حسب: A.M. Kettlun, وآخرون
منشور في: (2000-07-01)

Identification of the high-affinity tolbutamide site on the SUR1 subunit of the K(ATP) channel.
حسب: Ashfield, R, وآخرون
منشور في: (1999)

Activation of the K(ATP) channel by Mg-nucleotide interaction with SUR1.
حسب: Proks, P, وآخرون
منشور في: (2010)

Effects of protein phosphorylation on the sulphonylurea receptor of the pancreatic beta-cell.
حسب: Niki, I, وآخرون
منشور في: (1997)

Interactions between tolbutamide and nucleotides on cloned K-ATP channels.
حسب: Gribble, F, وآخرون
منشور في: (1997)

Characterization of two novel forms of the rat sulphonylurea receptor SUR1A2 and SUR1BDelta31.
حسب: Gros, L, وآخرون
منشور في: (2002)

Crystallographic details of the nucleotide-binding pocket of subunit A and B of A-ATP synthases and insight into the nucleotide-binding subunit α of the Escherichia coli F-ATP synthases
حسب: Vikeramjeet Singh Tadwal
منشور في: (2011)

ATP/ADP binding to a novel nucleotide binding domain of the reticulocyte-binding protein Py235 of Plasmodium yoelii
حسب: Ramalingam, Jeya Kumar, وآخرون
منشور في: (2011)

Direct photoaffinity labeling of Kir6.2 by [gamma-(32)P]ATP-[gamma]4-azidoanilide.
حسب: Tanabe, K, وآخرون
منشور في: (2000)

Nucleotide binding to the ATP-cone in anaerobic ribonucleotide reductases allosterically regulates activity by modulating substrate binding
حسب: Ornella Bimai, وآخرون
منشور في: (2024-07-01)

New uses for old drugs: neonatal diabetes and sulphonylureas.
حسب: Ashcroft, F
منشور في: (2010)

Identification of the high affinity tolbutamide site on the SUR1 subunit of the K-ATP channel
حسب: Gribble, F, وآخرون
منشور في: (1999)

Mechanism of action of a sulphonylurea receptor SUR1 mutation (F132L) that causes DEND syndrome.
حسب: Proks, P, وآخرون
منشور في: (2007)

Investigation of Protonation Effects on ATP Binding in ABC Transporters
حسب: Aittoniemi, J, وآخرون
منشور في: (2010)

Conserved inhibitory mechanism and competent ATP binding mode for adenylyltransferases with Fic fold.
حسب: Arnaud Goepfert, وآخرون
منشور في: (2013-01-01)

Activation and inhibition of K-ATP currents by guanine nucleotides is mediated by different channel subunits.
حسب: Trapp, S, وآخرون
منشور في: (1997)

Mapping the architecture of the ATP-binding site of Kir6.2
حسب: Dabrowski, M, وآخرون
منشور في: (2002)

Review. SUR1: a unique ATP-binding cassette protein that functions as an ion channel regulator.
حسب: Aittoniemi, J, وآخرون
منشور في: (2009)

Subunit F modulates ATP binding and migration in the nucleotide-binding subunit B of the A1AO ATP synthase of Methanosarcina mazei Gö1
حسب: Raghunathan, Devanathan, وآخرون
منشور في: (2013)

Characterisation of sulphonylurea and ATP-regulated K+ channels in rat pancreatic A-cells.
حسب: Bokvist, K, وآخرون
منشور في: (1999)