Single-molecule protein phosphorylation and dephosphorylation by nanopore enzymology

Reversible protein phosphorylation plays a crucial and ubiquitous role in the control of almost all cellular processes. The interplay of protein kinases and phosphatases acting in opposition ensures tight dynamic control of protein phosphorylation states within the cell. Previously, engineered alpha...

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Bibliographic Details
Main Authors: Harrington, L, Alexander, LT, Knapp, S, Bayley, H
Format: Journal article
Language:English
Published: American Chemical Society 2018