Molecular modifiers of T cell antigen receptor triggering threshold: the mechanism of CD28 costimulatory receptor.
CD28 was thought to represent a prototypic membrane receptor responsible for delivering the classically defined 'second signal' needed to avoid T cell paralysis when recognizing antigen presented by appropriate antigen presenting cells (APCs). Almost two decades after its molecular identif...
Main Authors: | , , , |
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Format: | Journal article |
Language: | English |
Published: |
2003
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