Mechanisms and evolutionary patterns of mammalian and avian dosage compensation

Mechanisms and evolutionary patterns of mammalian and avian dosage compensation

As a result of sex chromosome differentiation from ancestral autosomes, male mammalian cells only contain one X chromosome. It has long been hypothesized that X-linked gene expression levels have become doubled in males to restore the original transcriptional output, and that the resulting X overexp...

Полное описание

Библиографические подробности
Главные авторы:	Julien, P, Brawand, D, Soumillon, M, Necsulea, A, Liechti, A, Schütz, F, Daish, T, Grützner, F, Kaessmann, H
Формат:	Journal article
Язык:	English
Опубликовано:	Public Library of Science 2012

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