Muscarinic and nicotinic receptors raise intracellular Ca2+ levels in rat carotid body type I cells.

1. The effects of cholinergic agonists upon intracellular free Ca2+ levels ([Ca2+]i) have been studied in enzymically isolated rat carotid body single type I cells, using indo-1. 2. Acetylcholine (ACh) dose-dependently increased [Ca2+]i in 55% of cells studied (EC50 = 13 microM). These [Ca2+]i rises...

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Bibliographic Details
Main Authors: Dasso, L, Buckler, K, Vaughan-Jones, R
Format: Journal article
Language:English
Published: 1997