A novel adaptor protein orchestrates receptor patterning and cytoskeletal polarity in T-cell contacts.

Recognition of antigen by T cells requires the formation of a specialized junction between the T cell and the antigen-presenting cell. This junction is generated by the recruitment and the exclusion of specific proteins from the contact area. The mechanisms that regulate these events are unknown. He...

Full description

Bibliographic Details
Main Authors: Dustin, M, Olszowy, M, Holdorf, A, Li, J, Bromley, S, Desai, N, Widder, P, Rosenberger, F, van der Merwe, P, Allen, P, Shaw, A
Format: Journal article
Language:English
Published: Cell Press 1998