A novel adaptor protein orchestrates receptor patterning and cytoskeletal polarity in T-cell contacts.
Recognition of antigen by T cells requires the formation of a specialized junction between the T cell and the antigen-presenting cell. This junction is generated by the recruitment and the exclusion of specific proteins from the contact area. The mechanisms that regulate these events are unknown. He...
Main Authors: | Dustin, M, Olszowy, M, Holdorf, A, Li, J, Bromley, S, Desai, N, Widder, P, Rosenberger, F, van der Merwe, P, Allen, P, Shaw, A |
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Format: | Journal article |
Language: | English |
Published: |
Cell Press
1998
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