Forced expression of the cyclin B1-CDC2 complex induces proliferation in adult rat cardiomyocytes
Repair of the mature mammalian myocardium following injury is impaired by the inability of the majority of cardiomyocytes to undergo cell division. We show that overexpression of the cyclin B1-CDC2 (cell division cycle 2 kinase) complex re-initiates cell division in adult cardiomyocytes. Thus strate...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2004
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