Preparation of bead-supported lipid bilayers to study the particulate output of t cell immune synapses

Antigen-presenting cells (APCs) present three activating signals to T cells engaged in physical contact: 1) antigen, 2) costimulation/corepression, and 3) soluble cytokines. T cells release two kinds of effector particles in response to activation: trans-synaptic vesicles (tSVs) and supramolecular a...

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Bibliographic Details
Main Authors: Céspedes, PF, Dustin, ML
Format: Journal article
Language:English
Published: MyJove Corporation 2022