Preparation of bead-supported lipid bilayers to study the particulate output of t cell immune synapses
Antigen-presenting cells (APCs) present three activating signals to T cells engaged in physical contact: 1) antigen, 2) costimulation/corepression, and 3) soluble cytokines. T cells release two kinds of effector particles in response to activation: trans-synaptic vesicles (tSVs) and supramolecular a...
Main Authors: | Céspedes, PF, Dustin, ML |
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Format: | Journal article |
Language: | English |
Published: |
MyJove Corporation
2022
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