Relative contributions of insulin deficiency and insulin resistance in maturity-onset diabetes.

The effects of raised insulin resistance and decreased beta-cell function on basal plasma glucose and insulin concentrations have been estimated by means of a mathematical model which uses the available data on control of glucose and insulin flux. The model shows that near-normal basal plasma insuli...

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Bibliographic Details
Main Authors: Turner, R, Mathews, DR, Holman, R, Peto, J
Format: Journal article
Language:English
Published: 1982