Homochiral lithium amides for the asymmetric synthesis of beta-amino acids
Secondary homochiral lithium amides derived from α-methylbenzylamine undergo highly diastereoselective conjugate additions to a range of α,β-unsaturated esters. The corresponding β-amino acids are readily liberated by successive N-debenzylation and ester hydrolysis, furnishing (R)-β-amino butyric ac...
मुख्य लेखकों: | , , , , , , , , |
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स्वरूप: | Journal article |
भाषा: | English |
प्रकाशित: |
2006
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