Antidepressant drug treatment induces Arc gene expression in the rat brain.
The mechanism underlying the therapeutic effect of antidepressants is not known but neuroadaptive processes akin to long-term potentiation have been postulated. Arc (Activity-regulated, cytoskeletal-associated protein) is an effector immediate early gene implicated in LTP and other forms of neuropla...
Egile Nagusiak: | , , , , |
---|---|
Formatua: | Journal article |
Hizkuntza: | English |
Argitaratua: |
2003
|