Enamines from terminal epoxides and hindered lithium amides.
A new reactivity mode of lithium amides with epoxides leads to hindered enamines. The reaction of some of these enamines with unactivated primary and secondary alkyl halides is described, which expands the range of electrophiles that one can use in the synthesis of mono-alkylated aldehydes.
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2004
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