cGMP-phosphodiesterase inhibition prevents hypoxia-induced cell death activation in porcine retinal explants

Retinal hypoxia and oxidative stress are involved in several retinal degenerations including diabetic retinopathy, glaucoma, central retinal artery occlusion, or retinopathy of prematurity. The second messenger cyclic guanosine monophosphate (cGMP) has been reported to be protective for neuronal cel...

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Bibliographic Details
Main Authors: Olivares-González, L, Martinez-Fernandez de la Camara, C, Hervás, D, Marín, MP, Lahoz, A, Millán, JM, Rodrigo, R
Format: Journal article
Language:English
Published: Public Library of Science 2016