Novel interactions of volatile anaesthetics on O2 sensing and TASK channels in carotid body type-1 cells

<p>Hypoxia elicits a carotid body-mediated increase in minute ventilation, called the chemoreflex. Volatile anaesthetics depress this chemoreflex, even at sub-anaesthetic doses. The broad aim of this thesis is to explore how these anaesthetics act on carotid body mechanisms to depress the c...