Glucose stimulates the entry of Ca2+ into the insulin-producing beta cells but not into the glucagon-producing alpha 2 cells.

Rat pancreatic beta and alpha 2 cells were purified by autofluorescence-activated cell sorting and used for electrophysiological patch clamp studies and measurements of the initial uptake of 45Ca. Both beta and alpha 2 cells were electrically active, the action potentials of the latter cells also we...

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Bibliographic Details
Main Authors: Wesslén, N, Pipeleers, D, Van de Winkel, M, Rorsman, P, Hellman, B
Format: Journal article
Language:English
Published: 1987