Targeting acid ceramidase to improve the radiosensitivity of rectal cancer

Previous work utilizing proteomic and immunohistochemical analyses has identified that high levels of acid ceramidase (AC) expression confers a poorer response to neoadjuvant treatment in locally advanced rectal cancer. We aimed to assess the radiosensitising effect of biological and pharmacological...

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Bibliographic Details
Main Authors: Clifford, R, Govindarajah, N, Bowden, D, Sutton, P, Glenn, M, Darvish-Damavandi, M, Buczacki, S, McDermott, U, Szulc, Z, Ogretmen, B, Parsons, J, Vimalachandran, D
Format: Journal article
Language:English
Published: MDPI 2020