Toxicity and efficacy of 6-thioguanine versus 6-mercaptopurine in childhood lymphoblastic leukaemia: a randomised trial.

BACKGROUND: 6-mercaptopurine has been a standard component of long-term continuing treatment for childhood lymphoblastic leukaemia, whereas 6-thioguanine has been mainly used for intensification courses. Since preliminary data have shown that 6-thioguanine is more effective than 6-mercaptopurine, we...

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Detalles Bibliográficos
Autores principales: Vora, A, Mitchell, C, Lennard, L, Eden, T, Kinsey, SE, Lilleyman, J, Richards, S
Formato: Journal article
Lenguaje:English
Publicado: 2006