Alpha-thalassemia caused by a large (62 kb) deletion upstream of the human alpha globin gene cluster.

Alpha-thalassemia caused by a large (62 kb) deletion upstream of the human alpha globin gene cluster.

We describe a family in which alpha-thalassemia occurs in association with a deletion of 62 kilobases from a region upstream of the alpha globin genes. DNA sequence analysis has shown that the transcription units of both alpha genes downstream of this deletion are normal. Nevertheless, they fail to...

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Príomhchruthaitheoirí:	Hatton, C, Wilkie, A, Drysdale, H, Wood, W, Vickers, M, Sharpe, J, Ayyub, H, Pretorius, I, Buckle, V, Higgs, D
Formáid:	Journal article
Teanga:	English
Foilsithe / Cruthaithe:	1990

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