Genetic associations of type 2 diabetes with islet amyloid polypeptide processing and degrading pathways in asian populations

Type 2 diabetes (T2D) is a complex disease characterized by beta cell dysfunctions. Islet amyloid polypeptide (IAPP) is highly conserved and co-secreted with insulin with over 40% of autopsy cases of T2D showing islet amyloid formation due to IAPP aggregation. Dysregulation in IAPP processing, stabi...

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Bibliographic Details
Main Authors:	Lam, V, Ma, R, Lee, H, Hu, C, Park, K, Furuta, H, Wang, Y, Tam, C, Sim, X, Ng, D, Liu, J, Wong, T, Tai, E, Morris, A, Tang, N, Woo, J, Leung, P, Kong, A, Ozaki, R, Jia, W, Nanjo, K, Xu, G, Ng, M, So, W, Chan, J
Format:	Journal article
Language:	English
Published:	Public Library of Science 2013

Genetic associations of type 2 diabetes with islet amyloid polypeptide processing and degrading pathways in asian populations

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