Smooth-muscle myosin mutations in hereditary non-polyposis colorectal cancer syndrome.

We examined adenomas and cancers from hereditary non-polyposis colorectal cancer (HNPCC) syndrome patients for the presence of frameshift mutations in the smooth-muscle myosin gene, MYH11. Our results show that mutations in MYH11 occur more frequently in cancers than adenomas (P=0.008) and are depen...

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מידע ביבליוגרפי
Main Authors: Vickaryous, N, Polanco-Echeverry, G, Morrow, S, Suraweera, N, Thomas, H, Tomlinson, I, Silver, A
פורמט: Journal article
שפה:English
יצא לאור: 2008