A bump and hole approach to the development of selective degrons

<p>The aim of this study was to develop novel immunomodulatory imide drug (IMiD) analogues which would not induce degradation of endogenous proteins but would induce degradation of a suitably modified zinc finger (ZF) degron motif, therefore providing an IMiD/ZF degron system that could be rel...

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Bibliographic Details
Main Author: Brennan, PJ
Other Authors: Conway, S
Format: Thesis
Language:English
Published: 2023
Subjects: