A bump and hole approach to the development of selective degrons

<p>The aim of this study was to develop novel immunomodulatory imide drug (IMiD) analogues which would not induce degradation of endogenous proteins but would induce degradation of a suitably modified zinc finger (ZF) degron motif, therefore providing an IMiD/ZF degron system that could be rel...

Täydet tiedot

Bibliografiset tiedot
Päätekijä: Brennan, PJ
Muut tekijät: Conway, S
Aineistotyyppi: Opinnäyte
Kieli:English
Julkaistu: 2023
Aiheet: