A bump and hole approach to the development of selective degrons
<p>The aim of this study was to develop novel immunomodulatory imide drug (IMiD) analogues which would not induce degradation of endogenous proteins but would induce degradation of a suitably modified zinc finger (ZF) degron motif, therefore providing an IMiD/ZF degron system that could be rel...
Main Author: | Brennan, PJ |
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Other Authors: | Conway, S |
Format: | Thesis |
Language: | English |
Published: |
2023
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Subjects: |
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