Epigenetic potentiation of somatostatin-2 by guadecitabine in neuroendocrine neoplasias as a novel method to allow delivery of peptide receptor radiotherapy

<p><strong>Background:&nbsp;</strong>Somatostatin receptor-2 (SSTR2) is expressed on cell surface of neuroendocrine neoplasias; its presence is exploited for the delivery of peptide receptor radionuclide therapy (PRRT). Patients with no or low expression of SSTR2 are not candid...

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Bibliographic Details
Main Authors: Evans, JS, Beaumont, J, Braga, M, Masrour, N, Mauri, F, Beckley, A, Butt, S, Karali, CS, Cawthorne, C, Archibald, S, Aboagye, EO, Sharma, R
Format: Journal article
Language:English
Published: Elsevier 2022