CD103+ tumor-infiltrating lymphocytes are tumor-reactive intraepithelial CD8+ T cells associated with prognostic benefit and therapy response in cervical cancer.
Human papilloma virus (HPV)-induced cervical cancer constitutively expresses viral E6/E7 oncoproteins and is an excellent target for T cell-based immunotherapy. However, not all tumor-infiltrating T cells confer equal benefit to patients, with epithelial T cells being superior to stromal T cells. To...
المؤلفون الرئيسيون: | Komdeur, F, Prins, T, van de Wall, S, Plat, A, Wisman, G, Hollema, H, Daemen, T, Church, D, de Bruyn, M, Nijman, H |
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التنسيق: | Journal article |
اللغة: | English |
منشور في: |
Taylor and Francis
2017
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مواد مشابهة
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