Identification and characterisation of homologous recombination genes in Schizosaccharomyces pombe
<p>DNA double-strand breaks (DSBs) are highly genotoxic lesions, which can promote chromosomal rearrangements and tumorigenesis through oncogene activation or loss of heterozygosity (LOH) at tumour suppressor loci. To identify new genes involved in DSB repair and genome stability, an S. pombe...
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Format: | Thesis |
Language: | English |
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2011
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