Bistability by multiple phosphorylation of regulatory proteins.

The activity of a protein can be reversibly modulated by post-translational, covalent modifications, such as phosphorylation and dephosphorylation. In many cases, the modulated protein may be phosphorylated by the same kinase on many different amino acid residues. Such multisite phosphorylations may...

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Bibliographic Details
Main Authors: Kapuy, O, Barik, D, Sananes, MR, Tyson, J, Novák, B
Format: Journal article
Language:English
Published: 2009