Dissociation of gp120 from HIV-1 virions induced by soluble CD4.
The CD4 antigen is the high affinity cellular receptor for the human immunodeficiency virus type-1 (HIV-1). Binding of recombinant soluble CD4 (sCD4) or the purified V1 domain of sCD4 to the surface glycoprotein gp120 on virions resulted in rapid dissociation of gp120 from its complex with the trans...
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1990
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