Synthetic tools for studying the chemical biology of InsP8
To synthesise stabilised mimics of InsP8, the most phosphorylated inositol phosphate signalling molecule in Nature, we replaced its two diphosphate (PP) groups with either phosphonoacetate (PA) or methylenebisphosphonate (PCP) groups. Utility of the PA and PCP analogues was verified by structural an...
Main Authors: | , , , |
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Format: | Journal article |
Language: | English |
Published: |
Royal Society of Chemistry
2015
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