Synthetic tools for studying the chemical biology of InsP8

To synthesise stabilised mimics of InsP8, the most phosphorylated inositol phosphate signalling molecule in Nature, we replaced its two diphosphate (PP) groups with either phosphonoacetate (PA) or methylenebisphosphonate (PCP) groups. Utility of the PA and PCP analogues was verified by structural an...

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書目詳細資料
Main Authors: Riley, A, Wang, H, Shears, S, Potter, BVL
格式: Journal article
語言:English
出版: Royal Society of Chemistry 2015