Reduced serotonin 5-HT1A receptor binding in the temporal cortex correlates with aggressive behavior in Alzheimer disease.

Previous studies have implicated brain serotonin 5-HT(1A) receptors in several CNS functions, including cognition, mood and emotional states. In Alzheimer disease (AD), cognitive impairment and behavioral symptoms are the main clinical features. However, the biochemical basis of such changes is poor...

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Bibliographic Details
Main Authors: Lai, M, Tsang, S, Francis, P, Esiri, M, Keene, J, Hope, T, Chen, C
Format: Journal article
Language:English
Published: 2003