Regioselective Dieckmann cyclisations leading to enantiopure highly functionalised tetramic acid derivatives
Regioselective Dieckmann cyclisations using an N-acyloxazolidine derived from L-serine give substituted tetramic acids in high yield and enantioselectivity. The products are easily deprotected under mild conditions to give hydroxymethyltetramic acids.
Bibliographic Details
| Main Authors: |
Andrews, MD,
Brewster, A,
Crapnell, K,
Ibbett, A,
Jones, T,
Moloney, M,
Prout, K,
Watkin, D |
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| Format: | Journal article
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| Language: | English |
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| Published: |
1998
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